In the pharmaceutical industry, Adrenochrome is an oxidation product of Adrenaline (Epinephrine). As a pharmacist and manufacturer, it is important to clarify that while “Adrenochrome” itself is an unstable research chemical with no approved clinical use, its stable derivative—Adrenochrome Monosemicarbazone (Carbazochrome)—is a well-established hemostatic medication.
At your WHO-GMP facility in Mumbai, you would likely deal with the stable Carbazochrome form used to control capillary bleeding.
Price Analysis (India Market)
The price varies significantly based on the formulation (Tablet vs. Injection) and the brand. Below is a market snapshot:
| Dosage Form | Strength | Approx. Price (INR) | Common Brands |
| Oral Tablet | 1 mg / 10 mg | ₹5 – ₹120 per strip | Stepza, Styptocid |
| Injection | 1 mg / 5 mg | ₹5 – ₹35 per vial/ampoule | Sigmachrome, Chromostat |
| Research Grade | Pure Powder | ₹4,500+ per 25 mg | Sigma-Aldrich / ChemImpex |
Primary Clinical Uses (as Carbazochrome)
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Capillary Hemorrhage: Used to stop oozing from small blood vessels during and after surgery (e.g., tonsillectomy, dental extractions).
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Hematuria: Effective in managing blood in the urine.
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Retinal Hemorrhage: Used in ophthalmology to control micro-bleeds in the eye.
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Epistaxis: Management of severe or persistent nosebleeds.
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Secondary Wound Bleeding: Used preoperatively to reduce the risk of excessive bleeding.
Mechanism of Action: Capillary Stabilization
Carbazochrome does not affect the systemic coagulation cascade (like Warfarin or Heparin); instead, it acts directly on the microvasculature.
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Vessel Contraction: It stimulates alpha-adrenergic receptors on the blood vessels, causing the smooth muscles of the small arterioles and capillaries to contract (narrow).
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Reduced Permeability: It reduces capillary fragility and “leakiness,” effectively stopping the oozing of blood from raw surfaces.
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Clot Promotion: While it doesn’t create a clot itself, by slowing the flow of blood at the site of injury, it allows the body’s natural fibrin mesh to form more effectively.
The Manufacturer’s Perspective: Technical & Export
From a production and B2B standpoint at your facility in Mumbai, there are several key technical points to consider:
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Adrenochrome vs. Carbazochrome: On your digital platforms and multivendor marketplace, always use the term Carbazochrome or Adrenochrome Monosemicarbazone for medical listings. Using “Adrenochrome” alone can trigger conspiracy-related filters or attract non-medical traffic.
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Stability Challenges: Adrenochrome is highly unstable and light-sensitive (photolabile). The monosemicarbazone form is used specifically to ensure a stable 36-month shelf life.
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Packaging for Export: For export to Zone IVb (tropical) regions, we utilize Amber-colored ampoules and Alu-Alu blister packaging to protect the API from UV light and oxidation.
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Dossier Support: As this is an essential hemostatic agent, we maintain full CTD/eCTD Dossiers to support your firm’s registration for hospital supply tenders and international NGO contracts.