What is Zinc Sulphate tablets 20 mg used for?

In the pharmaceutical industry, Zinc Sulphate 20 mg is a vital mineral supplement and an essential component of global health protocols. As a pharmacist and manufacturer, I classify this as a “life-saving micronutrient,” particularly in pediatric care.While zinc is found in many multivitamins, the 20 mg standalone tablet is specifically designed for therapeutic intervention rather than general nutrition.

Primary Clinical Uses

  • Pediatric Diarrhea Management: This is the most critical use. The WHO and UNICEF recommend 20 mg of zinc daily for 10–14 days for children with acute diarrhea to reduce the duration, severity, and risk of recurrence.

  • Zinc Deficiency Treatment: Used to treat confirmed deficiency (hypozincemia) caused by malnutrition, chronic malabsorption (like Celiac or Crohn’s disease), or long-term parenteral nutrition.

  • Wound Healing: Zinc is essential for collagen synthesis and cell division; it is often prescribed to accelerate the healing of chronic ulcers, burns, and surgical incisions.

  • Immune System Support: Used as an adjuvant therapy in chronic infections or for patients with weakened immune responses.

    Acrodermatitis Enteropathica: Treatment for this rare genetic disorder that prevents the body from absorbing enough zinc from the diet.

Mechanism of Action: The Cellular Architect

Zinc does not work on a single organ; it is a co-factor for over 300 different enzymes in the human body.

Intestinal Epithelial Integrity: In diarrhea, zinc helps “tighten” the junctions between cells in the gut lining and stimulates the immune response, helping the body clear the infection faster.

DNA & Protein Synthesis: It is required for the function of “Zinc Finger Proteins,” which are essential for reading genetic code and building new cells.

T-Cell Function: Zinc is crucial for the maturation of T-lymphocytes. Without it, the body’s “cellular” immunity effectively shuts down.

Carbonic Anhydrase Activity: It supports the enzyme responsible for CO2 transport and pH balance in the blood.

The Manufacturer’s Perspective: Technical & Export

From a production and B2B standpoint at your WHO-GMP facility in Mumbai, Zinc Sulphate 20 mg is a high-volume, high-impact product:

  • Dispersible Tablet (DT) Technology: For pediatric export, the “Gold Standard” is the Dispersible Tablet. It must dissolve in a teaspoon of water or breast milk within 60 seconds. At our facility, we use specialized “super-disintegrants” (like Crospovidone) to ensure this. Marketing this as “DT” on your digital platform is a major USP for NGO tenders.

  • Taste Masking: Zinc Sulphate is naturally metallic and bitter, which causes “vomiting” in children. We utilize advanced flavoring agents (usually vanilla or fruit) and sweeteners to ensure the child completes the full 14-day course.

  • Stability & Moisture: Zinc Sulphate is highly hygroscopic (absorbs moisture from the air). To maintain a 36-month shelf life in Zone IVb (tropical) climates, we utilize Alu-Alu blister packaging to provide an absolute moisture barrier.

  • Global Tenders: This product is a staple for UNICEF, The Global Fund, and National Health Missions. We provide full CTD/eCTD Dossiers to support your firm in bidding for these large-scale international supply contracts.

How many tablets of Zinc Sulphate per day?

In the pharmaceutical industry, Zinc Sulphate tablets (most commonly manufactured in 20 mg elemental zinc strength) are classified as a vital mineral supplement. As a pharmacist and manufacturer, I view this product as a cornerstone of global public health, particularly in the management of pediatric gastrointestinal disorders and immune system optimization.

Primary Clinical Uses

  • Acute and Persistent Diarrhea (Pediatric): The WHO and UNICEF recommend Zinc Sulphate as a standard treatment for children. It reduces the duration and severity of the episode and prevents future episodes for up to 2–3 months.

  • Zinc Deficiency: Treatment of nutritional deficiency caused by inadequate diet, malabsorption syndromes (like Crohn’s disease), or chronic liver and kidney disease.

  • Wound Healing: Used to speed up the healing of gastric ulcers, pressure sores, and surgical wounds, as zinc is essential for tissue repair.

  • Immune System Support: Often prescribed as an adjuvant therapy for recurrent respiratory tract infections.

  • Acrodermatitis Enteropathica: A rare genetic disorder where the body cannot absorb enough zinc; lifelong high-dose Zinc Sulphate is the primary treatment.

Mechanism of Action: Restoring the Gut & Immunity

Zinc acts as a “molecular signal” and a structural component for over 300 enzymes in the body.

Intestinal Integrity: Zinc restores mucosal barrier integrity and increases the levels of enzymes in the intestinal “brush border” that help absorb water and electrolytes.

Ion Channel Regulation: It acts as a potassium channel blocker, which inhibits the secretion of chloride into the gut—effectively stopping the “watery” component of diarrhea.

Protein Synthesis: Zinc is a critical cofactor for DNA polymerase and RNA polymerase, making it indispensable for the rapid cell division required to heal the gut lining and produce white blood cells.

The Manufacturer’s Perspective: Technical & Export

From a production and B2B standpoint at your WHO-GMP facility in Mumbai, Zinc Sulphate is one of the most stable and high-demand export assets:

  • The Dispersible Tablet (DT) USP: For your e-commerce and B2B platforms, the 20 mg Dispersible Tablet is the gold standard. It must disintegrate in less than 60 seconds in a teaspoon of water. Marketing this “Rapid-Dissolve” technology is key for international NGO contracts.

  • Overcoming the Metallic Taste: As a pharmacist, you know zinc has a harsh, metallic taste that can cause children to vomit. At our facility, we utilize specialized taste-masking agents and fruit flavors (like strawberry or vanilla) to ensure high patient compliance.

  • Hygroscopic Challenges: Zinc Sulphate is highly sensitive to moisture. To maintain a 36-month shelf life for export to Zone IVb (tropical) climates, we utilize Alu-Alu blister packaging to provide an absolute moisture barrier.

    Calculating “Elemental” Zinc: For technical accuracy on your website, always specify the conversion: Zinc Sulphate Monohydrate 54.9 mg is equivalent to 20 mg of Elemental Zinc. Providing this level of detail builds trust with international distributors.

 

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