In the pharmaceutical industry, Ascorbic Acid (Vitamin C) tablets (commonly available in 100 mg, 500 mg, and 1000 mg) are the most widely recognized essential water-soluble vitamins. As a pharmacist, I view Vitamin C not just as a supplement, but as a vital cofactor for collagen synthesis and a primary biological antioxidant that protects cellular components from oxidative stress.

Primary Clinical Uses

• Treatment of Scurvy: The definitive treatment for Vitamin C deficiency, characterized by capillary fragility, bleeding gums, and impaired wound healing.

• Immune System Enhancement: Used to support both innate and adaptive immune functions. It stimulates the production and function of white blood cells (leukocytes) and acts as a barrier against pathogens.

• Iron Absorption: Frequently co-prescribed with iron supplements to treat anemia, as Vitamin C significantly enhances the absorption of non-heme iron in the gastrointestinal tract.

• Supportive Therapy: Used to promote wound healing post-surgery, treat pressure sores, and manage chronic infections where oxidative stress is high.

Mechanism of Action

Ascorbic Acid acts as an electron donor for eight different enzymes. Its most critical role is in collagen hydroxylation, where it stabilizes the triple helix of collagen fibers, providing structural integrity to skin, blood vessels, and bones. As a potent antioxidant, it neutralizes reactive oxygen species (ROS), thereby preventing damage to DNA, proteins, and lipids.

The Manufacturer’s Perspective: Formulation & Export

From a manufacturing and global trade standpoint, Vitamin C is a high-volume product that requires specialized environmental controls:

• Oxidation Control: Ascorbic Acid is highly sensitive to light, heat, and moisture, which causes it to turn yellow or brown. As a WHO-GMP manufacturer, we utilize strictly controlled RH (Relative Humidity) environments and opaque packaging to prevent degradation.

• Chewable & Effervescent Varieties: To improve patient compliance, we focus on chewable tablets with advanced taste-masking for its natural acidity, as well as effervescent tablets for rapid absorption and better “mouthfeel.”

• Global Export Staple: Vitamin C is a consistent top-seller in B2B marketplaces and international tenders. Our Mumbai-based facility provides customized strengths and packaging (strip/blister/bulk bottles) for the African, CIS, and Southeast Asian markets.

• Quality Standards: We ensure all batches comply with BP/USP/IP monographs, specifically testing for “Related Substances” and “Assay” to guarantee the 24-month shelf life required for international shipping.