What is vitamin B1 vitamin B2 vitamin B6 vitamin B12 Niacinamide calcium pantothenate tablets?
In the pharmaceutical industry, this combination of Vitamin B1, B2, B3 (Niacinamide), B5 (Calcium Pantothenate), B6, and B12 is known as a High-Potency Therapeutic B-Complex.
As a pharmacist and manufacturer, I view this as a “metabolic powerhouse.” While each vitamin has a specific role, they are combined because they act as interdependent co-enzymes that unlock energy from food and maintain the integrity of the central and peripheral nervous systems.
Clinical Uses & Benefits
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Treatment of B-Complex Deficiency: Addresses symptoms like glossitis (tongue inflammation), cheilosis (cracked corners of the mouth), and stomatitis.
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Neuroprotection: Indicated for peripheral neuropathy, neuralgia, and “pins and needles” sensations, particularly in diabetic or alcoholic patients.
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Convalescence: Essential for patients recovering from surgery, chronic infections, or long-term antibiotic therapy (which can deplete gut-synthesized B-vitamins).
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Metabolic Support: Used to manage fatigue and weakness by optimizing the conversion of carbohydrates, fats, and proteins into cellular energy (ATP).
Mechanism of Action: The Mitochondrial Engine
This combination targets the Krebs Cycle (Citric Acid Cycle), the primary energy-producing process in every cell of the body.
B1, B2, and B3 (Niacinamide): These are the “Primary Converters.” They act as electron carriers (NAD/FAD) that move energy through the mitochondrial membrane to produce ATP.
B5 (Calcium Pantothenate): A precursor to Coenzyme A, which is necessary for the synthesis of fatty acids and the maintenance of the myelin sheath (nerve insulation).
B6 and B12: These are the “Cell Builders.” They are required for heme synthesis (red blood cells) and the maintenance of nerve fibers. B12 specifically prevents “short-circuits” in nerve transmission.
The Manufacturer’s Perspective: Technical & Export
From a production standpoint at your WHO-GMP facility in Mumbai, this product is a cornerstone for international trade:
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Formulation Stability: B-vitamins are notoriously sensitive to moisture and light. To ensure a 36-month shelf life for export to Zone IVb (tropical) climates, we utilize Alu-Alu blister packaging.
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Odor Masking: Thiamine (B1) has a strong sulfurous smell. We utilize advanced Film Coating technology to provide an odorless, easy-to-swallow tablet, which is a significant USP (Unique Selling Proposition) for your retail brand.
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The “Yellow Urine” Factor: As a pharmacist, you should include in your Product Information Leaflet (PIL) that Riboflavin (B2) naturally colors urine bright yellow. Explaining this to B2B clients builds clinical authority.
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Dossier Readiness: Since this is a staple “Essential Medicine,” we maintain full CTD/eCTD Dossiers to support your firm’s registration in various global markets, from Southeast Asia to Africa.