In the pharmaceutical industry, the combination of Dried Aluminium Hydroxide Gel, Magnesium Hydroxide, and Simethicone is the definitive “Triple Action” formulation for upper gastrointestinal relief.As a pharmacist and manufacturer, I classify this as an Antacid and Anti-flatulent combination. At your WHO-GMP facility in Mumbai, this is a high-volume OTC (Over-the-Counter) asset, often marketed as the generic version of brands like Mylanta or Digene.

Primary Clinical Uses

• Hyperacidity: Neutralizes excess stomach acid to provide rapid relief from “heartburn” and acid indigestion.

• Peptic Ulcer & Gastritis: Used as an adjuvant therapy to soothe the stomach lining and reduce the corrosive effect of acid on ulcers.

• GERD (Gastroesophageal Reflux Disease): Helps manage symptoms of acid reflux.

• Flatulence & Meteorism: Specifically addresses the “bloated” feeling by breaking down trapped gas in the digestive tract.

• Dyspepsia: General relief for an upset stomach caused by overeating or spice-heavy diets.

Mechanism of Action: The Balanced Neutralizer

This formulation is scientifically “balanced” to provide relief while minimizing the side effects common in single-ingredient antacids.

Aluminium Hydroxide: A slow-acting antacid that provides prolonged neutralization. Technical note: It is known to cause constipation.

Magnesium Hydroxide: A fast-acting antacid that neutralizes acid quickly. Technical note: It is known to have a laxative effect.

The “Synergy” (Al + Mg): By combining these two, we achieve a neutral effect on bowel movements, preventing both constipation and diarrhea—a major selling point for your B2B clients.

Simethicone: An anti-foaming agent. It lowers the surface tension of gas bubbles in the stomach and intestines, causing them to coalesce into larger bubbles that are easier to pass (via burping or flatus).

The Manufacturer’s Perspective: Technical & Export

From a production standpoint at your facility in Mumbai, this chewable tablet is a strategic “Brand-Building” product:

• The Chewable Advantage: For your e-commerce and marketplace platforms, you must highlight that chewing the tablet increases the surface area of the antacid, allowing it to neutralize acid much faster than a swallowed pill.

• Flavoring Technology: Antacids naturally have a “chalky” or “gritty” mouthfeel. At our facility, we utilize specialized micronized powders and fruit flavors (Mint, Orange, or Mixed Fruit) to ensure a smooth, pleasant taste, which is critical for repeat retail customers.

• Stability & Moisture Control: Simethicone is an oily liquid that must be adsorbed onto a solid carrier. We ensure strict adsorption uniformity to prevent the tablets from becoming “spotted” or unstable over their 36-month shelf life.

• Dossier Support: As a WHO-GMP manufacturer, we provide full CTD/eCTD Dossiers. This is a top-selling product for hospital supply tenders and pharmacies in the Middle East, Africa, and Southeast Asia.