Description

Medroxyprogesterone Acetate Injection

Healthy Inc is a specialized global supplier and exporter of long-acting progestogen therapies. We provide high-purity Medroxyprogesterone Acetate Injection (150 mg / 1 ml), sourced from WHO–GMP certified sterile injectable facilities. This “Three-Month Protection” specialist is a top export to family planning clinics, gynecology centers, and government health ministries in Africa, LATAM, and Southeast Asia, serving as the global standard for long-term reversible contraception and the management of endometriosis.

Product Overview

This formulation contains Medroxyprogesterone Acetate (MPA), a synthetic derivative of 17-hydroxyprogesterone that acts as a potent progestational agent.

The “Depot” Specialist:

• Mechanism (Triple Protection): MPA prevents pregnancy through three distinct actions:
  • Ovulation Inhibition: It suppresses the secretion of gonadotropins, preventing the follicular maturation and the mid-cycle LH surge.
  • Cervical Mucus Thickening: It increases the viscosity of cervical mucus, creating a barrier that is impenetrable to sperm.
  • Endometrial Alteration: It thins the lining of the uterus, making it unfavorable for embryo implantation.
• Extended Release: As an aqueous suspension, the crystals at the injection site dissolve slowly, maintaining therapeutic blood levels for 13 weeks (3 months).
• Non-Contraceptive Benefits: It is highly effective in reducing the pain associated with endometriosis and managing abnormal uterine bleeding.

Product Composition & Strength

We supply this product as a Sterile Aqueous Suspension in glass vials or prefilled syringes.

*Pack Sizes: Single Vial with Syringe, or Tray of 25/50 Vials for Tenders.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Particle Size Engineering: The 3-month duration depends entirely on the crystal size of the MPA. Our manufacturing uses Micronization technology to ensure a uniform particle size distribution, preventing “burst release” and ensuring a steady, predictable contraceptive effect.
• Resuspendability: Our formulation is designed to ensure the sedimented cake easily disperses into a uniform white suspension with minimal shaking, ensuring the full dose is administered.

Therapeutic Indications (Human Use)

Indicated for long-term hormonal management:

• Contraception: Prevention of pregnancy for 13 weeks per dose.
• Endometriosis: Management of pain and lesions.
• Oncology (High Dose): Adjunctive and palliative treatment of endometrial or renal carcinoma.
• Vasomotor Symptoms: Management of menopausal symptoms in specific patient profiles.

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Deep Intramuscular (IM) Injection (Gluteal or Deltoid) or Subcutaneous (SC) depending on the formulation.
• Contraception: 150 mg every 3 months (13 weeks). The first injection should be given during the first 5 days of a normal menstrual cycle.
• Post-Partum: If not breastfeeding, can be given within 5 days post-partum. If breastfeeding, wait until 6 weeks post-partum.
• Administration: SHAKE VIGOROUSLY before use to ensure a uniform suspension.

Safety Warnings (CRITICAL):

• Bone Mineral Density (BMD) Loss: Long-term use (>2 years) is associated with a decrease in BMD. Use with caution in adolescent patients.
• Delayed Return to Fertility: It may take 6 to 12 months after the last injection for ovulation to resume. Patients should be counseled on this delay.
• Irregular Bleeding: Breakthrough bleeding or spotting is common during the first few months. Amenorrhea (absence of periods) often occurs after 1 year of use.
• Weight Gain: Significant weight gain is a reported side effect in many users.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Hormonal Suspensions, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.