Description
Indapamide Tablets
Healthy Inc is a specialized global supplier and exporter of metabolically neutral antihypertensive agents. We provide high-purity Indapamide Tablets (Immediate Release and Sustained Release), sourced from WHO–GMP certified solid dosage facilities. This “Dual-Action” diuretic is a top export to stroke prevention units, diabetic care centers, and government health formularies in Africa, LATAM, and Southeast Asia, recognized as the superior thiazide-like diuretic for long-term blood pressure control without lipid or glucose disruption.
Product Overview
This formulation contains Indapamide, a sulphonamide derivative with both diuretic and calcium-antagonist-like properties.
The “Vascular Protective” Specialist:
- Dual Mechanism:
- Natriuretic Effect: Like thiazides, it acts on the distal convoluted tubule (DCT) of the kidney to excrete sodium and water, reducing blood volume.
- Vasodilatory Effect (Unique): Unlike standard thiazides, Indapamide directly relaxes the smooth muscle of blood vessels (arterioles) by regulating calcium ion influx and stimulating prostacyclin synthesis. This reduces peripheral resistance significantly.
- Metabolic Neutrality: It is “Lipid Neutral” (does not raise cholesterol) and “Glucose Neutral” (does not affect insulin sensitivity), making it the Diuretic of Choice for Diabetics and patients with metabolic syndrome.
- Stroke Reduction: Clinical trials (like HYVET) have established Indapamide as a gold standard for preventing strokes in elderly hypertensive patients.
Product Composition & Strength
We supply this product as Sugar/Film Coated Tablets (Immediate Release) or Sustained Release (SR) Tablets.
| Active Ingredient | Strength | Formulation | Role |
|---|---|---|---|
| Indapamide USP/BP | 1.5 mg | Sustained Release (SR) | Modern Standard Dose (24hr Control) |
| Indapamide USP/BP | 2.5 mg | Immediate Release | Classic Maintenance Dose |
| Excipients | Q.S. | HPMC (Matrix) / Lactose | Release Control |
*Pack Sizes: Blister packs of 10s, 15s, 30s (Calendar Pack), or Bulk HDPE Jars of 1000s.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Other Medicaments) |
| Dosage Form | Tablet (Coated / SR) |
| Packaging | PVC-Alu Blister or Alu-Alu Blister |
| Storage | Store below 25°C. Keep in a dry place. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- SR Matrix Technology: The 1.5 mg SR tablet utilizes a hydrophilic matrix system. Upon contact with GI fluid, the polymer swells to form a gel layer, controlling the diffusion of the drug to ensure consistent blood pressure reduction over a full 24-hour period.
- Content Uniformity: Due to the low dosage (1.5 mg), we use advanced geometric blending to ensure every tablet contains the exact amount of API, preventing dose dumping or sub-therapeutic failure.
Therapeutic Indications (Human Use)
Indicated for the treatment of:
- Essential Hypertension: Used as monotherapy or in combination with other antihypertensive agents (e.g., Perindopril or Amlodipine).
- Left Ventricular Hypertrophy (LVH): Proven to regress the thickening of the heart muscle caused by chronic high blood pressure.
- Edema: Treatment of salt and fluid retention associated with congestive heart failure (less common use today).
Dosage & Administration
Recommended Dosage (Strictly as per Cardiologist):
- Route: Oral.
- Sustained Release (1.5 mg): One tablet daily, preferably in the morning. Swallow whole; do not chew or crush.
- Immediate Release (2.5 mg): One tablet daily, in the morning.
- Timing: Morning administration is recommended to avoid nocturia (waking up at night to urinate), although the diuretic effect of Indapamide is milder than Furosemide.
Safety Warnings:
- Electrolyte Imbalance: Can cause Hypokalemia (low potassium). Regular monitoring of serum potassium is required, especially in elderly patients.
- Sulfa Allergy: Indapamide is a sulfonamide derivative. Contraindicated in patients with severe sulfa allergies.
- Uric Acid: Can reduce uric acid excretion, potentially triggering gout attacks in susceptible individuals.
- Photosensitivity: May cause sensitivity to sunlight.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
