Description

Fluconazole Capsules

Healthy Inc is a specialized global supplier and exporter of advanced anti-fungal, gynecological, and infectious disease therapeutics. We provide high-purity, highly bioavailable Fluconazole Capsules (50 mg / 150 mg / 200 mg), manufactured in WHO–GMP certified, high-capacity oral solid dosage facilities. This “First-Line Triazole Antifungal” is a massive-volume, essential export to gynecology clinics, retail pharmacy networks, HIV/AIDS NGOs, and government health ministries in LATAM, the Middle East, Africa, and Southeast Asia, serving as the globally trusted intervention for vulvovaginal candidiasis, severe systemic fungal infections, and cryptococcal meningitis.

Product Overview

This formulation contains Fluoxetine Hydrochloride (Correction: Fluconazole) Fluconazole, a highly potent, broad-spectrum synthetic triazole that aggressively targets fungal cell walls while maintaining a vastly superior safety profile compared to older antifungals like Ketoconazole.

The “Systemic Fungal Eradication” Specialist:

• Mechanism (Ergosterol Depletion): Fungi rely absolutely on a molecule called ergosterol to maintain the structural integrity of their cell membranes. Fluconazole binds to and aggressively inhibits the fungal enzyme lanosterol 14-α-demethylase, completely halting ergosterol production. This causes the fungal cell membrane to become highly porous, leak vital cellular contents, and halt replication (fungistatic at normal doses, fungicidal at high doses).
• The “One-Pill” Gynecology Champion (150mg): For acute vulvovaginal candidiasis (yeast infections), a single 150mg oral dose of Fluconazole provides a clinical cure rate equivalent to a full week of messy topical creams. This unparalleled convenience makes it one of the highest-velocity OTC/Retail pharmacy dispensing items in the world.
• The HIV/AIDS Lifesaver (200mg): In severely immunocompromised patients, the Cryptococcus fungus can infect the brain, causing fatal meningitis. Fluconazole crosses the blood-brain barrier exceptionally well, making it the globally mandated prophylactic and maintenance therapy for cryptococcal meningitis in HIV/AIDS wards.

Product Composition & Strength

We supply this product as a Hard Gelatin Capsule, packed in highly secure, moisture-resistant Alu-PVC or opaque Alu-Alu blister strips, optimized for both single-dose retail dispensing and chronic institutional therapy.

*Pack Sizes: Highly specialized 1×1 Blisters (for the 150mg Retail Gynecology market), and standard 10×10 Blisters for hospital/NGO infectious disease wards.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Gynecology Distributors, and NGOs.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Exceptional Bioavailability Engineering: Fluconazole is renowned for having an oral bioavailability exceeding 90%. Our excipient matrix and blending parameters ensure the capsule ruptures and dissolves almost immediately in the gastric fluid, perfectly mimicking the pharmacokinetic absorption profile of an intravenous (IV) dose without the need for needles.
• 1×1 Mono-Carton Capability: For the 150mg retail market, we offer advanced, automated blistering that isolates a single capsule into a high-quality retail mono-carton, perfectly optimized for private pharmacy chains and high-margin OTC-equivalent sales.

Therapeutic Indications (Human Use)

Indicated for the comprehensive management of superficial and deep-tissue fungal infections:

• Vulvovaginal Candidiasis: Rapid, single-dose eradication of acute vaginal yeast infections.
• Oropharyngeal & Esophageal Candidiasis: Treatment of severe oral thrush, particularly in patients with asthma (using corticosteroid inhalers), dentures, or HIV/AIDS.
• Cryptococcal Meningitis: Acute treatment and long-term suppressive maintenance in immunocompromised patients.
• Systemic Candidiasis: Treatment of candidemia, disseminated candidiasis, and candida peritonitis.

Dosage & Administration

Recommended Dosage (Strictly as per Physician/Gynecologist):

• Administration: Can be taken orally, with or without food, as its absorption is not affected by gastric pH or meal composition.
• Single-Dose Gynecology: 150 mg as a single oral dose.
• Systemic Infections: Often requires a massive loading dose (e.g., 400 mg on day one), followed by 200 mg daily for several weeks, closely monitored by an infectious disease specialist.

Safety Warnings (CRITICAL):

• Hepatotoxicity: Fluconazole has been associated with rare cases of serious hepatic toxicity, including fatalities, primarily in patients with severe underlying medical conditions. Liver function must be monitored during prolonged, high-dose therapy.
• Cardiac Arrhythmias (QT Prolongation): Like many azole antifungals, Fluconazole can prolong the QT interval on an ECG. It is strictly contraindicated for co-administration with other drugs known to prolong the QT interval (such as Erythromycin or Pimozide) due to the risk of fatal Torsades de Pointes.
• Pregnancy Warning: While a single 150mg dose is generally considered safe, high-dose, continuous Fluconazole therapy during the first trimester of pregnancy has been linked to severe, rare congenital birth defects.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Retail Pharmacy Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Antifungal Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable NGO Tender Supplier for HIV opportunistic infections in Africa or a B2B Pharma Marketplace partner for Southeast Asia, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.