In the pharmaceutical industry, Haloperidol is a high-potency typical antipsychotic belonging to the butyrophenone class. As a pharmacist and manufacturer, I can confirm that Haloperidol is not a sleeping pill; it is primarily used to treat schizophrenia, manic episodes, and acute psychoses.
While it does cause sedation as a side effect, it is not prescribed for primary insomnia because of its significant impact on the central nervous system and the risk of movement disorders.
At your WHO-GMP facility in Mumbai, you likely handle this in 0.25 mg to 20 mg tablets, or as a fast-acting lactate injection for hospital use.
Primary Clinical Indications
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Schizophrenia: Management of positive symptoms like hallucinations and delusions.
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Acute Psychosis: Rapid control of agitation and aggressive behavior.
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Tourette’s Syndrome: Used to reduce severe motor and vocal tics.
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Intractable Hiccups: Used as a second-line treatment when other therapies fail.
Mechanism: Dopamine () Receptor Antagonism
Receptor Blockade: Haloperidol works by strongly binding to and blocking Dopamine receptors in the brain.
Mesolimbic Pathway: By blocking these receptors in the mesolimbic area, it reduces the overactive dopamine signaling responsible for psychotic symptoms.
Sedative Side Effect: The sedation occurs as a secondary effect of its action on the CNS, but unlike true “sleeping pills” (hypnotics), it does not target the GABA system.
The Pharmacist’s “Technical Warning”
As you promote your firm on digital platforms, highlighting these technical nuances is essential for professional authority:
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Extrapyramidal Symptoms (EPS): Because it is a high-potency blocker, it has a high risk of causing movement disorders like tremors, muscle stiffness (dystonia), and restlessness (akathisia).
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QT Prolongation: It can affect the heart’s electrical rhythm; patients with pre-existing heart conditions must be monitored via ECG.
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Tardive Dyskinesia: Long-term use can lead to irreversible, involuntary movements of the face and tongue.
The Manufacturer’s Perspective: Technical & Export
From a production and B2B standpoint at your facility in Mumbai:
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Precision Manufacturing: Haloperidol is active at very low doses (e.g., 0.25 mg). Your Content Uniformity and blending validation must be impeccable. Highlighting this on your marketplace shows high technical competence.
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Hospital Portfolios: Highlight your Haloperidol Lactate 5mg/ml Injections for emergency psychiatry departments. These are essential “Rescue Medications” in hospital settings.
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Stability for Export: Haloperidol is light-sensitive. Utilizing Amber-colored PVC/PVDC or Alu-Alu blister packaging ensures a 36-month shelf life in Zone IVb tropical regions.
Dossier Support: We provide full CTD/eCTD Dossiers to support your firm’s registration in international health tenders.