Teicoplanin for Injection

Healthy Inc is a specialized global supplier and exporter of advanced antimicrobial and critical care therapies. We provide high-purity Teicoplanin for Injection (200 mg / 400 mg), manufactured in WHO–GMP certified sterile lyophilization facilities. This “Extended-Half-Life Glycopeptide” is a mandatory export to intensive care units (ICU), orthopedic centers, and government health ministries in Africa, LATAM, and Southeast Asia, serving as a top-tier, definitive intervention for severe, multi-drug resistant Gram-positive infections, including Methicillin-Resistant Staphylococcus aureus (MRSA).

Product Overview

This formulation contains Teicoplanin, a complex of five highly structurally related bactericidal glycopeptide antibiotics derived from the fermentation of Actinoplanes teichomyceticus.

The “Gram-Positive / MRSA” Specialist:

• Mechanism (Cell Wall Blockade): Like Vancomycin, Teicoplanin physically binds to the D-alanyl-D-alanine terminus of the cell wall precursor units. This massive macromolecule acts as a steric shield, blocking the transglycosylase and transpeptidase enzymes from cross-linking the peptidoglycan layer. The bacterial cell wall rapidly weakens, leading to osmotic lysis and cell death.
• The Vancomycin Alternative: Teicoplanin offers major clinical upgrades over older glycopeptides. It is highly lipophilic, giving it an exceptionally long terminal half-life (up to 168 hours). After an initial loading-dose phase, it allows for highly convenient once-daily dosing. Furthermore, it does not induce histamine release, completely eliminating the risk of “Red Man Syndrome” associated with rapid Vancomycin infusions.
• Intramuscular (IM) Capability: Unlike Vancomycin (which causes severe tissue necrosis if given IM), Teicoplanin is well-tolerated via deep intramuscular injection, making it an invaluable option for outpatient parenteral antimicrobial therapy (OPAT) or in settings where central venous access is unavailable.

Product Composition & Strength

We supply this product as a Sterile Lyophilized Powder (Spongy, Ivory to Pale Yellow Cake) in glass vials, accompanied by a specific sterile diluent.

*Pack Sizes: 1 Vial of Lyophilized Powder + 1 Ampoule of Diluent (3 ml) per box.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Macromolecule Lyophilization: Teicoplanin is a massive, complex fermentation product. Our lyophilization cycle is strictly calibrated to preserve the structural integrity of all five glycopeptide components, ensuring a highly porous cake that reconstitutes smoothly without irreversible clumping.
• Aseptic Grade A Processing: Because this is a last-line defense for septic patients, the powder is aseptically filled and sealed under Grade A laminar airflow to ensure absolute sterility and a 100% pyrogen-free profile for direct intravenous bolus or central line infusion.

Therapeutic Indications (Human Use)

Indicated for the treatment of severe infections caused by susceptible Gram-positive bacteria (including methicillin-resistant staphylococci and enterococci):

• Complicated Skin and Soft Tissue Infections (cSSSI): Severe cellulitis, abscesses, and surgical wound infections.
• Bone and Joint Infections: Osteomyelitis and septic arthritis (Teicoplanin has excellent bone penetration).
• Hospital-Acquired Pneumonia (HAP): Including ventilator-associated pneumonia caused by MRSA.
• Infective Endocarditis & Septicemia: Aggressive bloodstream infections requiring prolonged therapy.

Dosage & Administration

Recommended Dosage (Strictly as per Infectious Disease Specialist):

• Route: Intravenous (IV) Bolus, IV Infusion, or Intramuscular (IM) Injection.
• Loading Dose Protocol (CRITICAL): To achieve rapid therapeutic serum concentrations, Teicoplanin requires a loading regimen. Typically, 400 mg (or 6 mg/kg) every 12 hours for the first 3 doses.
• Maintenance Dose: Following the loading phase, a maintenance dose of 400 mg (or 6 mg/kg) is given once daily.
• Administration Warning (Foaming): When adding the diluent, slowly inject it down the side of the vial. DO NOT SHAKE. Gently roll the vial between the palms until the powder is completely dissolved to prevent excessive foam formation, which makes drawing the dose difficult.
• IV Bolus: Can be injected directly into the vein over 3 to 5 minutes (unlike Vancomycin, which requires a slow 60-minute infusion).

Safety Warnings (CRITICAL):

• Cross-Sensitivity: Patients with a history of hypersensitivity to Vancomycin may experience cross-reactivity with Teicoplanin; use with extreme caution.
• Thrombocytopenia: High doses or prolonged use (beyond typical therapy durations) carry a risk of severe thrombocytopenia (low platelet count). Complete blood counts (CBC) must be monitored during extended treatment.
• Nephrotoxicity & Ototoxicity: While statistically less nephrotoxic and ototoxic than Vancomycin, concurrent use with other toxic drugs (like Aminoglycosides, e.g., Tobramycin) synergistically increases the risk of renal failure and hearing loss.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Critical Care Antibiotics, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.