Cefuroxime Sodium Injection
Healthy Inc is a specialized global supplier and exporter of robust Second-Generation Cephalosporins. We provide high-purity Cefuroxime Sodium Injection (750 mg / 1.5 g), sourced from WHO–GMP certified sterile injectable facilities. This “Community-Acquired Specialist” is a top export to pulmonology clinics, orthopedic surgery centers, and government health ministries in Africa, LATAM, and Southeast Asia, serving as the primary defense against respiratory tract infections and as a versatile surgical prophylaxis agent.
Product Overview
This formulation contains Cefuroxime Sodium, a second-generation cephalosporin distinguished by its resistance to beta-lactamases produced by *Haemophilus influenzae* and *Moraxella catarrhalis*.
The “Dual-Zone” Specialist:
- Respiratory Potency: Unlike first-generation cephalosporins, Cefuroxime has excellent activity against Gram-negative respiratory pathogens like H. influenzae and Klebsiella, making it the drug of choice for severe pneumonia and bronchitis.
- Surgical Prophylaxis: It is widely used for preventing infections in “clean-contaminated” surgeries (e.g., cardiac, thoracic, and orthopedic procedures) because it covers both skin flora (Staph) and potential respiratory/gut contaminants.
- Lyme Disease: It is one of the few cephalosporins effective against Borrelia burgdorferi, making it a critical treatment for early Lyme disease (erythema migrans) and Lyme arthritis.
- CNS Penetration: Unlike Cefazolin, Cefuroxime can cross the blood-brain barrier when meninges are inflamed, providing coverage for Haemophilus meningitis (though 3rd gen is preferred now).
Product Composition & Strength
We supply this product as a Sterile Dry Powder for Injection in glass vials.
| Active Ingredient | Strength | Primary Use |
|---|---|---|
| Cefuroxime Sodium USP/BP | Equivalent to 750 mg Cefuroxime | Standard Adult Dose |
| Cefuroxime Sodium USP/BP | Equivalent to 1500 mg (1.5 g) | Severe Infections / Surgery |
| Excipients | None (Pure Sterile Powder) | – |
*Pack Sizes: Tray of 1 Vial, 10 Vials, 50 Vials, or Box of 1/10 Vials with Water for Injection (WFI).
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.20.19 (Medicaments containing other antibiotics) |
| Dosage Form | Powder for Injection (Dry Fill) |
| Packaging | Type I Glass Vial (Sterile) with Flip-off Seal |
| Storage | Store below 25°C. Protect from Light. Reconstituted solution stable for 24 hours at room temp (darkens upon standing). |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Crystalline Stability: Cefuroxime Sodium exists in different crystalline forms. We use a highly stable polymorph that ensures rapid solubility without forming a gel-like precipitate, a common issue in lower-quality generics.
- Color Consistency: The powder is naturally white to off-white. Our rigorous quality control ensures no thermal degradation occurs during filling, preventing the powder from turning yellow prematurely.
Therapeutic Indications (Human Use)
Indicated for the treatment of moderate to severe infections:
- Lower Respiratory Tract: Community-Acquired Pneumonia (CAP), acute bronchitis, lung abscess.
- Surgical Prophylaxis: Cardiac, vascular, orthopedic, and GI surgeries.
- Skin & Soft Tissue: Cellulitis, erysipelas, and wound infections.
- Bone & Joint: Septic arthritis and osteomyelitis (Staph/Strep).
- Lyme Disease: Early and late-stage bacterial infection.
- Urinary Tract: Pyelonephritis (asymptomatic bacteriuria).
Dosage & Administration
Recommended Dosage (Strictly as per Physician):
- Route: Intravenous (IV) Injection/Infusion or Deep IM.
- Adults: 750 mg to 1.5 g every 8 hours.
- Life-Threatening Infections: 1.5 g every 6 hours.
- Surgical Prophylaxis: 1.5 g IV given 30-60 minutes before incision. Can repeat 750 mg every 8 hours for 24 hours.
- Children: 50 to 100 mg/kg/day divided into 3-4 doses.
- Renal Impairment: Dose interval increased to every 12-24 hours if GFR < 20 ml/min.
- Reconstitution: Dissolve 750mg in 6ml WFI / 1.5g in 15ml WFI. Shake gently.
Safety Warnings (CRITICAL):
- Penicillin Allergy: CONTRAINDICATED in patients with a history of anaphylaxis to beta-lactams. Cross-sensitivity is approx 5-10%.
- Nephrotoxicity: Generally safe, but monitor renal function if used with potent diuretics (Furosemide) or aminoglycosides.
- Pain on Injection: IM injection is painful. Reconstitute with 1% Lidocaine for IM use only (NEVER IV).
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Sterile Injectables, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.