Healthy Inc > Products > Cefixime and Ofloxacin Tablets

Cefixime & Ofloxacin Film-Coated Tablets (200 mg / 200 mg)

Healthy Inc is a specialized global supplier and exporter of advanced anti-infectives, internal medicine, and targeted broad-spectrum therapeutics. We provide ultra-high-purity, kinetically balanced Cefixime & Ofloxacin Tablets (200 mg / 200 mg), manufactured in WHO–GMP certified, dedicated high-containment antibiotic facilities. This “3rd-Gen Cephalosporin & Fluoroquinolone FDC” is a massive-volume, highly strategic export to infectious disease clinics, fever hospitals, and government health ministries, serving as the globally preferred intervention for Enteric Fever (Typhoid), complicated Urinary Tract Infections (UTI), and severe Respiratory Tract Infections.

Product Overview

This formulation operates as a coordinated, two-front biochemical assault. By targeting two completely different essential systems within the bacteria—the structural cell wall and the internal genetic machinery—it ensures rapid bacterial eradication and significantly reduces the risk of the bacteria developing resistance.

  • Mechanism 1 (The Structural Executioner – Cefixime): Cefixime binds aggressively to Penicillin-Binding Proteins (PBPs). This halts the final transpeptidation step of peptidoglycan synthesis, causing the bacterial cell wall to lose its integrity and physically explode under osmotic pressure.

  • Mechanism 2 (The Genetic Saboteur – Ofloxacin): Ofloxacin is a potent fluoroquinolone that inhibits DNA Gyrase and Topoisomerase IV. These enzymes are mandatory for bacterial DNA replication, transcription, and repair. By paralyzing these enzymes, Ofloxacin prevents the bacteria from cloning itself.

  • Mechanism 3 (The Synergistic Spectrum): This combination is devastatingly effective against Salmonella typhi, H. influenzae, and E. coli. The dual-action approach ensures that even if a pathogen has a weak resistance to one class, the second class delivers the terminal blow.

Product Composition & Strength

We supply this product as a Precision-Blended, Bilayer or Co-Processed Tablet, packed in high-barrier Alu-Alu blister strips.

Active IngredientStrengthPrimary Clinical Function
Cefixime (as Trihydrate) USP/Ph.Eur.200 mgThe Extracellular Specialist: Targets the bacterial cell wall; highly effective against Gram-negative enteric pathogens.
Ofloxacin USP/Ph.Eur.200 mgThe Intracellular Specialist: Targets DNA replication; excellent tissue penetration into the lungs, prostate, and urinary tract.
ExcipientsProprietary MatrixBilayer Technology: Engineered to prevent physical interaction between the two APIs, ensuring maximum stability and a synchronized release profile in the gut.

Technical & Logistics Specifications

  • HS Code: 3004.20.00 (Medicaments containing antibiotics)

  • CAS Numbers: 79350-37-1 (Cefixime) / 82419-36-1 (Ofloxacin)

  • Dosage Form: Film-Coated Tablet (Immediate Release)

  • Packaging: Alu-Alu Blisters (STRICTLY MANDATORY). Both APIs are sensitive to environmental moisture. Alu-Alu packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

  • Dedicated Antibiotic Segregation: To prevent cross-contamination, production occurs in Strictly Isolated Antibiotic Blocks with independent air handling and pressure-controlled airlocks.

  • Dissolution Profiling: We utilize advanced multi-point dissolution testing to guarantee that both Cefixime and Ofloxacin are released at the optimal rate, ensuring bioequivalence to the market leaders.

Dosage & Administration

  • Standard Adult Dosing: 1 tablet taken twice daily (BID) for 7 to 14 days, depending on the severity of the infection.

  • The “Full Stomach” Recommendation: While absorption is high on an empty stomach, taking this FDC after a meal significantly reduces the gastric irritation and metallic taste often associated with Ofloxacin.

  • Hydration Mandate: Patients must drink plenty of fluids to prevent the formation of highly concentrated urine, which can lead to crystalluria.

Safety Warning: Strictly contraindicated in patients with a history of tendonitis or tendon rupture associated with fluoroquinolones. Use with caution in patients with epilepsy or renal impairment. Avoid concurrent use with antacids containing Magnesium or Aluminum, as they decrease Ofloxacin absorption by 90%.

Global Export & Contract Manufacturing

Healthy Inc is a premier Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume Antibiotic FDCs. Whether you are a Government Tender Supplier for typhoid eradication in Africa or a B2B Pharma Marketplace partner in the CIS, we ensure secure, WHO-GMP compliant delivery.

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