Acarbose Tablets
Healthy Inc is a specialized global supplier and exporter of metabolic control agents. We provide high-purity Acarbose Tablets, sourced from WHO–GMP certified solid dosage facilities. This “Carbohydrate Blocker” is a top export to diabetology clinics, endocrinology centers, and government health formularies in Africa, LATAM, and Southeast Asia, serving as a critical intervention for Type 2 Diabetes patients with high carbohydrate intake and significant post-prandial (after-meal) glucose spikes.
Product Overview
This formulation contains Acarbose, a complex oligosaccharide that acts as a competitive inhibitor of intestinal alpha-glucosidases.
The “Post-Prandial” Specialist:
- Mechanism (The Carb Brake): Acarbose works in the “brush border” of the small intestine. It reversibly binds to and inhibits the enzymes alpha-amylase (pancreatic) and alpha-glucosidase (intestinal). These enzymes are responsible for breaking down complex carbohydrates (starch, sucrose) into absorbable glucose.
- Delayed Digestion: By blocking these enzymes, Acarbose slows down the digestion of carbohydrates. Instead of a rapid spike in blood sugar immediately after eating, the release of glucose into the bloodstream is stretched out over a longer period.
- Insulin Sparing: Because it prevents the sharp “sugar spike,” it reduces the demand on the pancreas to produce a massive burst of insulin, protecting beta-cell function over time.
- Diet Suitability: It is exceptionally effective in populations with high-carbohydrate diets (rice, maize, bread staples), making it a preferred choice in Asian and African markets.
Product Composition & Strength
We supply this product as Uncoated Tablets. The dosing is highly dependent on patient tolerance to GI side effects.
| Active Ingredient | Strength (Standard) | Role |
|---|---|---|
| Acarbose USP/BP | 25 mg | Initiation Dose (To minimize gas) |
| Acarbose USP/BP | 50 mg | Standard Maintenance Dose |
| Acarbose USP/BP | 100 mg | High Carbohydrate Load Dose |
| Excipients | Q.S. | Microcrystalline Cellulose / Magnesium Stearate |
*Pack Sizes: Blister packs of 10s (Box of 10×10), 15s, 30s, or Bulk HDPE Jars of 500s.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Other Medicaments) |
| Dosage Form | Tablet (Oral) |
| Packaging | PVC-Alu Blister or Alu-Alu Blister (Hygroscopic) |
| Storage | Store below 25°C. Keep tightly sealed against moisture. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Fermentation Origin: Acarbose is produced via complex fermentation processes (actinomycetes). We ensure strict control over impurities and “Actinoplanes” by-products during the downstream processing to ensure a pure, safe API.
- Hygroscopicity: The API is highly hygroscopic (attracts water). Our manufacturing utilizes dehumidified environments to prevent the tablets from becoming soft or sticky, ensuring they remain stable in tropical distribution chains.
Therapeutic Indications (Human Use)
Indicated for the management of Type 2 Diabetes Mellitus:
- Monotherapy: As an adjunct to diet and exercise to lower blood glucose.
- Combination Therapy: Used with Metformin, Sulfonylureas, or Insulin to improve glycemic control, specifically targeting the post-prandial glucose spike that other drugs might miss.
- Pre-Diabetes: Sometimes used to delay the progression from Impaired Glucose Tolerance (IGT) to frank diabetes.
Dosage & Administration
Recommended Dosage (Strictly as per Endocrinologist):
- Route: Oral.
- The “First Bite” Rule (CRITICAL): Acarbose must be chewed with the first bite of the meal or swallowed whole with a little liquid immediately before the meal. If taken after the meal, it is ineffective because the enzymes have already started working.
- Titration (To reduce Flatulence):
- Start with 25 mg once daily (dinner) for 1-2 weeks.
- Increase to 25 mg three times daily.
- Titrate up to 50 mg or 100 mg three times daily as tolerated.
Safety Warnings:
- GI Side Effects (Very Common): Because undigested carbohydrates reach the colon, bacteria ferment them, causing flatulence (gas), bloating, and diarrhea. This usually subsides after 4-8 weeks as the gut adapts.
- Hypoglycemia Treatment: If a patient gets low blood sugar while on Acarbose, they must use Glucose (Dextrose) tablets or gel. Sucrose (Table Sugar) or Juice will NOT work fast enough because Acarbose blocks the breakdown of sucrose.
- Liver Enzymes: Rare elevations in liver enzymes can occur at high doses (200mg+). Monitoring is recommended.
- Contraindications: Inflammatory Bowel Disease (IBD), colonic ulceration, or partial intestinal obstruction.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in