Description

Sodium Picosulfate Tablets (10 mg)

Healthy Inc is a specialized global supplier and exporter of advanced gastroenterological, geriatric, and acute-care therapeutics. We provide ultra-high-purity, kinetically targeted Sodium Picosulfate Tablets (10 mg), manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Colonic-Targeted Stimulant Laxative” is a massive-volume, essential export to gastroenterology centers, geriatric care networks, retail pharmacy chains, and government health ministries in LATAM, the Middle East, Africa, and Southeast Asia, serving as the globally trusted, predictable intervention for acute and chronic constipation.

Product Overview

This formulation contains Sodium Picosulfate, a highly sophisticated prodrug that bypasses the stomach and small intestine entirely, specifically harnessing the body’s natural gut bacteria to trigger a bowel movement exactly where it is needed.

The “Colonic Flora Activated” Laxative Specialist:

• Mechanism (The Bacterial Prodrug Cleavage): When a patient swallows the tablet, it travels completely unabsorbed through the acidic stomach and the small intestine, causing zero upper gastrointestinal distress. Once it reaches the large intestine (colon), the resident gut bacteria cleave the molecule into its active form: bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).
• Targeted Peristalsis & Hydration: The newly formed BHPM vigorously stimulates the nerve endings in the mucosal wall of the colon. This physically forces the colon muscles to contract (peristalsis) while simultaneously increasing the secretion of water and electrolytes into the bowel lumen. This combination pushes the stool forward while keeping it soft, resulting in a highly predictable, comfortable bowel movement.
• The 6-to-12 Hour Clinical Window: Because the drug must travel all the way to the colon to be activated by bacteria, its onset of action is a highly predictable 6 to 12 hours. This makes it the ultimate “bedtime” laxative, allowing patients to take the tablet at night for guaranteed, reliable relief the following morning without disrupting their daily routine.

Product Composition & Strength

We supply this product as a Precision-Blended Uncoated or Film-Coated Tablet, packed in highly secure, moisture-resistant PVC/PVDC or Alu-PVC blister strips to ensure the stability of the active pharmaceutical ingredient.

*Pack Sizes: 10×10 Blisters (Optimized specifically for high-turnover retail pharmacy shelves and acute hospital dispensing).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, OTC Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Low-Dose Uniformity Engineering: Manufacturing a reliable 10 mg stimulant laxative requires precise low-dose geometric blending. If the active ingredient is not perfectly distributed throughout the powder matrix, patients could receive a sub-therapeutic dose (causing failure) or an artificially high dose (causing severe abdominal cramping and diarrhea). Our facilities utilize advanced high-shear granulation to guarantee absolute content uniformity in every single tablet.

Therapeutic Indications (Human Use)

Indicated for the targeted management of colonic motility disorders:

• Constipation: Short-term treatment of acute and chronic constipation of various etiologies (e.g., drug-induced, dietary, or age-related).
• Bowel Evacuation (Off-Label Adjunct): Sometimes utilized as an adjunctive therapy to evacuate the bowel prior to radiological procedures, endoscopy, or surgery.

Dosage & Administration

Recommended Dosage (Strictly as per Physician/Pharmacist Guidelines):

• Standard Adult Dosing: 5 mg to 10 mg (½ to 1 tablet) taken orally once a day.
• Administration (THE BEDTIME RULE): To produce a bowel movement the following morning, the tablet should be taken at night before retiring. It should be swallowed with an adequate amount of water.
• Duration of Use: Stimulant laxatives should generally not be used for more than 5 to 7 consecutive days without medical supervision.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• Hypokalemia & Electrolyte Imbalance: Prolonged or excessive use of Sodium Picosulfate forces the colon to excrete massive amounts of water and essential salts. This can lead to severe dehydration and dangerous Hypokalemia (low potassium in the blood), which can trigger fatal cardiac arrhythmias, especially in patients taking diuretics or digitalis.
• “Lazy Bowel” Syndrome (Dependency): Chronic daily use causes the colon muscles to lose their natural tone and become entirely dependent on the chemical stimulant to function, severely worsening long-term constipation.
• Acute Abdomen Contraindication (CRITICAL): Strictly contraindicated in patients suffering from undiagnosed severe abdominal pain, nausea, vomiting, intestinal obstruction (ileus), or acute inflammatory bowel diseases (like appendicitis or severe Crohn’s disease), as it can trigger a fatal intestinal rupture.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Retail Pharmacy Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Gastroenterological and OTC Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Pharmacy Chain Supplier for geriatric care programs in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.