Paracetamol Injection

Product Composition & Strength

We supply this product as a Sterile, Clear, Iso-osmotic Solution ready for direct intravenous infusion.

Active Ingredient	Concentration	Total Content & Format
Paracetamol BP/USP	10 mg / ml	1000 mg (1 g) in 100 ml Glass Bottle / FFS Plastic Bottle
Paracetamol BP/USP	150 mg / ml	300 mg in 2 ml Glass Ampoule (IM/IV use)
Excipients	Mannitol / Cysteine Hydrochloride	Isotonic Agent / Oxygen Scavenger (Antioxidant)

*Pack Sizes: 100 ml Single Bottle or Box of 10 Ampoules.

Paracetamol Injection

Healthy Inc is a specialized global supplier and exporter of essential critical care and pain management therapies. We provide high-purity Paracetamol IV Infusion (10 mg/ml / 1000 mg per 100 ml), manufactured in WHO–GMP certified sterile fluid facilities. This "First-Line Antipyretic & Analgesic" is a mandatory export to surgical wards, intensive care units (ICU), and government health ministries in Africa, LATAM, and Southeast Asia, serving as the gold standard for rapid pain relief and fever reduction when the oral route is compromised.

Product Overview

This formulation contains Paracetamol, a centrally acting, non-opioid, non-NSAID analgesic and antipyretic agent. The "Opioid-Sparing" Specialist:

• Mechanism (Central Inhibition): While its exact mechanism is still debated, Paracetamol primarily acts in the central nervous system (CNS). It inhibits the COX pathway (potentially COX-3) to reduce prostaglandin synthesis in the brain, effectively lowering the hypothalamic temperature set-point (antipyretic) and elevating the pain threshold (analgesic).
• Opioid-Sparing Effect: In post-operative care, administering IV Paracetamol significantly reduces the need for narcotic opioids (like Morphine or Fentanyl), thereby lowering the risk of respiratory depression, sedation, and post-operative nausea and vomiting (PONV).
• Hemodynamic Stability: Unlike NSAIDs (like Diclofenac or Ketorolac), Paracetamol does not inhibit peripheral COX-1 or COX-2 enzymes. It does not cause gastric irritation, impair platelet function (bleeding risk), or compromise renal blood flow, making it exceptionally safe for surgical patients.

Product Composition & Strength

We supply this product as a Sterile, Clear, Iso-osmotic Solution ready for direct intravenous infusion.

Active Ingredient	Concentration	Total Content & Format
Paracetamol BP/USP	10 mg / ml	1000 mg (1 g) in 100 ml Glass Bottle / FFS Plastic Bottle
Paracetamol BP/USP	150 mg / ml	300 mg in 2 ml Glass Ampoule (IM/IV use)
Excipients	Mannitol / Cysteine Hydrochloride	Isotonic Agent / Oxygen Scavenger (Antioxidant)

*Pack Sizes: 100 ml Single Bottle or Box of 10 Ampoules.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

HS Code	3004.90.99 (Medicaments containing other active substances)
Dosage Form	Solution for Infusion
Packaging	Type II Glass Bottle or Eurohead FFS (Form-Fill-Seal) Plastic Bottle.
Storage	Store below 30°C. Do Not Refrigerate or Freeze. Protect from light.
Certificates	WHO-GMP, COPP, Free Sale Certificate

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Oxidation Prevention: Paracetamol in an aqueous solution is highly susceptible to oxidation, which turns the liquid pink or brown. Our formulation utilizes specific antioxidants (like Cysteine) and our filling lines employ a strict Nitrogen Purging process to displace oxygen from the headspace, ensuring a stable 24-month shelf life.
• Sterility Assurance: Large volume parenterals (LVPs) are subjected to validated terminal sterilization via autoclaving, ensuring an absolute pyrogen-free status crucial for direct vascular access in vulnerable ICU patients.

Therapeutic Indications (Human Use)

Indicated for short-term treatment of moderate pain and hyperthermia:

• Post-Operative Analgesia: Immediate pain management following surgery.
• Severe Fever: Rapid reduction of hyperthermia in critical care or when oral administration is not feasible.
• Multimodal Analgesia: Used as a baseline analgesic in combination with opioids to manage severe acute pain.

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Intravenous (IV) Infusion ONLY. (For 100 ml bottle).
• Adults (>50 kg): 1000 mg (100 ml) up to 4 times a day.
• Minimum Interval: At least 4 hours between administrations.
• Maximum Daily Dose: Strictly 4 grams (4000 mg) per 24 hours.
• Infusion Time: Must be administered as a 15-minute intravenous infusion.

Safety Warnings (CRITICAL):

• Hepatotoxicity (Liver Damage): The primary risk of Paracetamol is liver failure due to overdose or accumulation. Ensure the 4g/day limit is not exceeded, accounting for all other medications that may contain acetaminophen.
• Weight-Based Dosing: In patients weighing less than 50 kg, chronic alcoholics, or those with severe renal/hepatic impairment, the maximum daily dose must be reduced to 3g/day or lower.
• Line Compatibility: Do not mix with other drugs in the same infusion line to avoid physical incompatibility.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Large Volume Parenterals (LVPs), allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates. https://healthyinc.co.in/product/paracetamol-injection-2/