Description

Diclofenac, Paracetamol & Serratiopeptidase Tablets

Healthy Inc is a specialized global supplier and exporter of advanced orthopedic, rheumatological, and acute-care analgesics. We provide ultra-high-purity, kinetically segregated Diclofenac Potassium (50 mg) + Paracetamol (325 mg) + Serratiopeptidase (10 mg Enteric-Coated) Tablets, manufactured in WHO–GMP certified, high-precision modified-release facilities. This “Triple-Action Anti-Inflammatory & Anti-Edema Synergy” is a massive-volume, high-priority export to orthopedic trauma centers, dental clinics, outpatient surgical wards, and government health ministries in LATAM, the Middle East, Africa, and Southeast Asia, serving as the globally trusted intervention for severe musculoskeletal pain and post-operative swelling.

Product Overview

This highly advanced Triple-FDC masterfully synchronizes a potent Non-Steroidal Anti-Inflammatory Drug (NSAID), a centrally acting analgesic, and a powerful biological proteolytic enzyme into a single, high-compliance surgical healing tablet.

The “Pain Eradication & Edema Drain” Specialist:

• Mechanism 1 (The Inflammatory Blocker – Diclofenac 50mg): Diclofenac aggressively inhibits both COX-1 and COX-2 enzymes at the site of tissue injury. This physically halts the production of prostaglandins—the chemical messengers that cause agonizing joint pain and severe inflammation. (We specifically utilize Diclofenac Potassium for its rapid absorption and faster onset of action compared to the Sodium salt).
• Mechanism 2 (The Central Analgesic – Paracetamol 325mg): While the NSAID works directly at the site of the injury, Paracetamol acts centrally within the brain and spinal cord to drastically elevate the patient’s pain threshold, providing a massive synergistic boost to the overall pain-killing effect.
• Mechanism 3 (The Proteolytic Edema Drain – Serratiopeptidase 10mg): This is the “magic bullet” of the formulation. Serratiopeptidase is an enzyme derived from the enterobacterium Serratia. It actively binds to the blood plasma and travels to the injury site, where it literally digests dead tissue, blood clots, and inflammatory fluids (like bradykinin and fibrin). By rapidly draining this localized fluid (edema), it physically removes the pressure from the surrounding nerves, vastly accelerating the surgical or traumatic healing process.

Product Composition & Strength

We supply this product as a Precision-Engineered Multi-Particulate Film-Coated Tablet, packed exclusively in highly secure, moisture-resistant Alu-Alu blister strips to ensure the absolute stability of the sensitive biological enzyme.

*Pack Sizes: 10×10 Alu-Alu Blisters (Optimized specifically for 5-to-7 day acute post-operative or trauma recovery regimens).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Orthopedic Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Enteric Enzymatic Segregation Engineering: This is a highly complex formulation. If Serratiopeptidase is exposed to the acidic environment of the stomach, it is instantly destroyed, rendering the drug useless. Our facilities utilize advanced Fluid Bed Processor (FBP) technology to coat the Serratiopeptidase powder with strict pH-dependent methacrylic polymers (Enteric Coating) before it is blended with the Diclofenac and Paracetamol. This guarantees the pain killers dissolve in the stomach for fast relief, while the enzyme safely bypasses the acid and releases perfectly in the alkaline intestine.

Therapeutic Indications (Human Use)

Indicated for the targeted eradication of severe pain accompanied by localized tissue swelling:

• Post-Operative Trauma: Pain and edema following orthopedic surgeries, dental extractions (e.g., impacted wisdom teeth), and maxillofacial surgeries.
• Musculoskeletal Trauma: Severe sports injuries, sprains, strains, fractures, and crush injuries.
• Gynecological & ENT Inflammations: Pelvic inflammatory disease, severe sinusitis, and tonsillitis where heavy edema is preventing antibiotic penetration.

Dosage & Administration

Recommended Dosage (Strictly as per Physician/Surgeon Guidelines):

• Standard Adult Dosing: One tablet taken 2 to 3 times a day (BID/TID), depending on the severity of the pain and swelling.
• Administration (THE MEALTIME RULE): To drastically reduce the risk of severe gastrointestinal ulceration caused by the Diclofenac component, this medication MUST be administered with or immediately after a full meal.
• Swallowing Protocol (CRITICAL HAZARD): The tablet MUST be swallowed whole with a glass of water. It must never be crushed, chewed, or divided. Chewing the tablet physically shatters the microscopic enteric coating on the Serratiopeptidase, exposing the enzyme to stomach acid and causing complete therapeutic failure of the anti-edema component.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• BLACK BOX WARNING (Cardiovascular Thrombosis): NSAIDs (including Diclofenac) massively increase the risk of serious, potentially fatal cardiovascular thrombotic events, myocardial infarction (heart attack), and stroke. Risk increases with duration of use and in patients with underlying cardiovascular disease. It is strictly contraindicated for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery.
• BLACK BOX WARNING (Gastrointestinal Bleeding): NSAIDs cause an increased risk of serious gastrointestinal adverse events, including bleeding, ulceration, and fatal perforation of the stomach or intestines.
• Hepatotoxicity (Paracetamol Overdose): Contains Paracetamol. Exceeding the absolute maximum daily limit of 4,000 mg of Paracetamol (from all dietary and pharmaceutical sources) can cause catastrophic, fatal acute liver failure. Avoid alcohol consumption.
• Bleeding Disorder Caution: Both Diclofenac (which affects platelets) and Serratiopeptidase (which breaks down fibrin clots) can prolong bleeding time. It must be used with extreme caution in patients with active bleeding disorders or those taking strong anticoagulants (like Warfarin).

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Retail Pharmacy Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Analgesic and Orthopedic Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for surgical wards in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.