Cefopodoxime Tablets

Product Composition & Strength

We supply this product as a Precision-Blended, High-Bioavailability Matrix, packed in high-barrier Alu-Alu blister strips.

Active Ingredient	Strength	Primary Clinical Function
Cefpodoxime Proxetil USP/Ph.Eur.	100 mg	The Pediatric & Titration Anchor: Ideal for Pharyngitis, Tonsillitis, and uncomplicated UTIs in adolescents and adults.
Cefpodoxime Proxetil USP/Ph.Eur.	200 mg	The Respiratory Macrodose: High-efficacy payload for Community-Acquired Pneumonia and Sinusitis.
Excipients	Proprietary Matrix	Solubility Enhancement: Engineered utilizing micronized API and specialized surfactants to overcome the naturally poor solubility of the Proxetil salt.

Cefopodoxime Tablets

Healthy Inc is a specialized global supplier and exporter of advanced anti-infectives, pediatric medicine, and targeted 3rd-generation cephalosporin therapeutics. We provide ultra-high-purity, kinetically optimized Cefpodoxime Proxetil Tablets (100 mg / 200 mg), manufactured in WHO–GMP certified, dedicated Beta-Lactam high-containment facilities. This "3rd-Generation Cephalosporin & Extended-Spectrum Antibiotic" is a massive-volume, premium export to pediatric hospitals, ENT clinics, and government health ministries, serving as the globally mandated intervention for community-acquired pneumonia, acute otitis media, and switch-therapy from IV Ceftriaxone.

Product Overview

This formulation operates as a structural saboteur of highly resilient bacteria. As a 3rd-generation agent, it possesses enhanced stability against $\beta$-lactamases and expanded coverage against Gram-negative pathogens that have developed resistance to older penicillins and 1st-gen cephalosporins.

• Mechanism 1 (The PBP-3 Target): Cefpodoxime binds with extreme affinity to Penicillin-Binding Proteins (PBPs), particularly PBP-3. This halts the cross-linking of the peptidoglycan layer during the final stages of bacterial cell wall assembly, causing the cell to lose its structural integrity.

• Mechanism 2 (The 3rd-Gen Spectrum): Unlike 1st or 2nd-gen agents, Cefpodoxime is devastatingly effective against Haemophilus influenzae, Moraxella catarrhalis, and Neisseria gonorrhoeae, making it a "Gold Standard" for complex respiratory and urinary infections.

• Mechanism 3 (The Proxetil Prodrug Kinetic): Cefpodoxime itself is poorly absorbed. The Proxetil ester makes the molecule lipophilic, ensuring high intestinal absorption. Once in the blood, esterases "unlock" the active Cefpodoxime, delivering a sustained, high-concentration bactericidal payload.

Technical & Logistics Specifications

• HS Code: 3004.20.00 (Medicaments containing antibiotics)

• CAS Number: 87239-81-4 (Cefpodoxime Proxetil)

• Dosage Form: Film-Coated Tablet (Immediate Release)

• Packaging: Alu-Alu Blisters (STRICTLY MANDATORY). Cefpodoxime Proxetil is highly sensitive to moisture and light. Alu-Alu packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Dedicated Beta-Lactam Containment: To prevent life-threatening cross-contamination, our production occurs in Strictly Isolated Beta-Lactam Blocks with dedicated HVAC and HEPA filtration systems.

• Micronization Engineering: We utilize advanced micronization technology to ensure a consistent particle size, guaranteeing uniform absorption and matching the pharmacokinetic profile of the originator brand.

Dosage & Administration

• Standard Adult Dosing: 100 mg to 200 mg every 12 hours for 5 to 14 days.

• The "Full Stomach" Rule: The bioavailability of Cefpodoxime Proxetil is significantly increased when taken with food. Taking this on an empty stomach may lead to sub-therapeutic blood levels.

• Gastric pH Warning: Absorption requires an acidic environment. Avoid concurrent use with strong antacids, H2-blockers, or PPIs, as they can reduce drug levels by up to 40%.

Safety Warning: Strictly contraindicated in patients with cephalosporin hypersensitivity. 10% cross-reactivity risk in penicillin-allergic patients. Monitor renal function in patients with severe impairment ($CrCl < 30$ mL/min).

Global Export & Contract Manufacturing

Healthy Inc is a premier Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for specialized Cephalosporins. Whether you are a Government Tender Supplier for child health in Africa or a B2B Pharma Marketplace partner in Southeast Asia, we ensure secure, WHO-GMP compliant delivery

https://healthyinc.co.in/product/cefpodoxime-proxetil-dispersible-tablets/