Description
Adapalene Gel (0.1% w/w / 0.3% w/w)
Healthy Inc is a specialized global supplier and exporter of advanced dermatology, aesthetic medicine, and targeted topical therapeutics. We provide ultra-high-purity, kinetically optimized Adapalene Gel, manufactured in WHO–GMP certified, high-precision specialized topical facilities. This “Third-Generation Polyaromatic Retinoid” is a massive-volume strategic export to dermatology hospitals, retail pharmacies, and government health ministries, serving as the globally preferred first-line intervention for Acne Vulgaris.
Product Overview
This formulation operates as a “Receptor-Specific Modulator.” Unlike older retinoids, Adapalene specifically targets the receptors responsible for skin cell differentiation, leading to fewer side effects like redness and peeling.
Mechanism 1 (Retinoid Receptor Selectivity): Adapalene binds specifically to the Retinoic Acid Receptors (RAR-β and RAR-γ) in the skin. This precision prevents the “over-activation” of inflammatory pathways seen with non-selective retinoids.
Mechanism 2 (Comedolytic Activity): It normalizes the differentiation of follicular epithelial cells. This physically prevents the formation of Microcomedones and “unplugs” existing pores by facilitating the shedding of dead skin cells.
Mechanism 3 (Anti-Inflammatory Action): It inhibits the chemotactic and chemokinetic responses of polymorphonuclear leukocytes. Physically, this means it reduces the redness and swelling of inflammatory acne lesions.
Product Composition & Strength
We supply Adapalene in a Water-Based, Alcohol-Free Gel, optimized for maximum stability and reduced skin irritation.
| Active Ingredient | Strength | Primary Clinical Function |
| Adapalene USP/BP/Ph.Eur. | 0.1% w/w | The Standard First-Line: Ideal for mild-to-moderate acne and long-term maintenance therapy. |
| Adapalene USP/BP/Ph.Eur. | 0.3% w/w | The High-Potency Option: Used for moderate-to-severe acne that is resistant to lower concentrations. |
| Excipients | Carbomer / Propylene Glycol | Aquasome Vehicle: Engineered to deliver the API deep into the follicle without greasy residue. |
Technical & Logistics Specifications
HS Code: 3004.90.99 (Medicaments acting on the skin – Retinoids)
CAS Number: 106685-40-9 (Adapalene)
Dosage Form: Topical Gel (Aqueous Base)
Packaging: Laminated Aluminum or Plastic Tubes (15g / 30g). Adapalene is more stable than Tretinoin, but our high-barrier packaging still ensures 24-month stability in Zone IVb tropical climates.
Manufacturing Authority & Compliance
Advanced Particle Engineering: Our manufacturing process focuses on the Micro-Micronization of Adapalene crystals, ensuring a smooth, grit-free gel that provides uniform drug delivery across the skin surface.
Photostability Excellence: Unlike 1st-generation retinoids, Adapalene does not degrade quickly in light. However, we still utilize UV-Filtered Production Zones to ensure the highest possible purity for export markets.
Primary Indications
Dermatology: Treatment of Acne Vulgaris (Grades I-III).
Maintenance: Prevention of new acne lesions after successful initial treatment.
Specialist Care: Management of comedonal acne (blackheads and whiteheads).
Dosage & Administration
Standard Regimen: Apply a thin film to the entire affected area once daily at bedtime.
Administration: Skin should be clean and dry. Avoid application to broken, eczematous, or sunburned skin.
Tolerance: Better tolerated than Tretinoin, making it suitable for patients with slightly sensitive skin.
Safety Warning: Sun Sensitivity. While more stable in light than other retinoids, Adapalene still increases the risk of sunburn. MANDATORY: Daily use of a broad-spectrum SPF 30+ sunscreen is required. Pregnancy: Generally not recommended during pregnancy (Category C). Avoid contact with eyes, lips, and mucous membranes.
Global Export & Contract Manufacturing
Healthy Inc is a premier Dermatology Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume Adapalene formulations. Whether you are a Skincare Brand in the Middle East or a B2B Pharma Marketplace partner in Africa, we ensure secure, WHO-GMP compliant delivery.
Commercial Inquiries:
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
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